Alpha-Fetoprotein: From a Diagnostic Biomarker to a Key Role in Female Fertility
نویسندگان
چکیده
منابع مشابه
Alpha-Fetoprotein: From a Diagnostic Biomarker to a Key Role in Female Fertility
Alpha-fetoprotein (AFP) is a well-known diagnostic biomarker used in medicine to detect fetal developmental anomalies such as neural tube defects or Down's syndrome, or to follow up the development of tumors such as hepatocellular carcinomas. However, and despite the fact that the protein was discovered almost half a century ago, little was known about its physiological function. The study of A...
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15 صفحه اولMONOCLONAL ANTIBODIES TO HUMAN ALPHA-FETOPROTEIN
Alpha-fetoprotein (AFP), a serum glycoprotein belonging to the onco-developmental proteins group, serves as a marker both in cancer research and in studies concerning fetal development and fetal pathophysiology. Monoclonal anti-AFP antibodies are essential reagents in developing appropriate techniques for measurement of this protein. In this study, in order to produce anti-AFP monoclonal a...
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MD, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo (UNIFESP), São Paulo SP, Brazil; MD, PhD, Department of Neurology and Neurosurgery, UNIFESP. Alpha-fetoprotein (AFP) is a fetal protein produced in the yolk sac and in the fetal liver. AFP has been implicated in both ontogenic and oncogenic growth disorders. Although the main biologic role of AFP during pregnancy re...
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ژورنال
عنوان ژورنال: Biomarker Insights
سال: 2006
ISSN: 1177-2719,1177-2719
DOI: 10.1177/117727190600100002